Prenatal exposure to genocide accelerates epigenetic aging in third- and fourth-generation clocks among young adults in Rwanda

Glorieuse Uwizeye, Luisa M Rivera, Hannah G Stolrow, Brock C Christensen, Julienne N Rutherford, Zaneta M Thayer

Prenatal exposure genocide-related to trauma has been previously associated with increased morbidity. Whether the prenatal exposure to genocide and rape also impacts various aspects of biological regulation, including patterns of DNA methylation, remains unknown. The purpose of this study was to evaluate whether prenatal exposure to genocide-related trauma, including conception through rape, is associated with accelerated epigenetic aging, a molecular indicator of biological aging.

Key wordsTransgenerational Trauma

CountriesGlobal

CategoryPublication